Fig. 2: Summary of characteristics of Mouse anti-GAS mAbs.

Vaccination strategies using antigens with no significant GAC or M protein have a white background; strategies using antigens containing GAC have a light green background; and strategies using antigens with no significant GAC but with M protein have a light blue background. Highlighting has also been used to emphasize mAbs that recognise GlcNAc-BSA (mid green background) and other antigens (mid blue background) as well as the level of cytotoxicity where tested (red background) and the number of mutations in the genes encoding the mAbs (brown). n.d. not determined.