Fig. 9: Representative electropherograms and summary graph showing the percentage integrity of mRNA in all analysed vaccine batches. | npj Vaccines

Fig. 9: Representative electropherograms and summary graph showing the percentage integrity of mRNA in all analysed vaccine batches.

From: Systematic analysis of COVID-19 mRNA vaccines using four orthogonal approaches demonstrates no excessive DNA impurities

Fig. 9

A Electropherogram of Comirnaty batch FP9632 with well preserved mRNA integrity. B Electropherogram of Comirnaty batch 1L084A with reduced mRNA integrity. C Graph summarising data from all analysed vaccine batches. The dashed line indicates 50% mRNA integrity. Each dot represents an individual vial (biological replicate), with values corresponding to the average of three capillary electrophoresis runs (technical replicates). Horizontal lines indicate the mean of three biological replicates, with error bars showing the standard deviation. Unexpired vaccine batches are marked with an asterisk.

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