Table 3 Key characteristics of the sequenced DNA fragments originating from plasmid genome

From: Systematic analysis of COVID-19 mRNA vaccines using four orthogonal approaches demonstrates no excessive DNA impurities

Vaccine batch

Read Count

Reads mapped to plasmid contig

Mapped reads proportion

Fragment size median

Fragment size average

FP9632

128 633 986

124 303 165

96.63%

161

183

1F1051A

128 754 938

126 281 087

98.08%

155

168

1L084A

114 100 030

109 945 922

96.36%

130

145

1F1059A

129 743 660

123 597 428

95.26%

134

147

PCB0020

110 126 612

105 815 251

96.09%

181

194

aLK8456

200 055 240

194 161 206

97.05%

165

183

aLK8842

195 186 178

188 261 908

96.45%

136

147

aLM9076

195 994 470

189 729 969

96.80%

170

188

aLN0605

198 887 382

192 564 352

96.82%

153

167

000058 A

103 869 046

90 339 760

86.97%

131

141

3005697

103 602 508

93 207 924

89.97%

201

226

200023 A

122 199 366

115 491 409

94.51%

142

153

200106 A

107 421 496

89 717 345

83.52%

132

143

MV1018A

96 552 136

88 102 825

91.25%

128

138

400012 A

102 951 692

88 568 921

86.03%

127

137

  1. Due to non-Gaussian read length distributions both median and average values are provided.
  2. aIndicate non-expired Comirnaty batches.