Table 4 Logistic regression analysis of the factors related to VBIs at 5 years old

From: Increased neonatal vaccine dose or booster immunization prevents hepatitis B vaccine breakthrough infection in children from HBsAg and HBeAg positive mothers

 

Univariate

 

Multivariate

 
 

OR (95% CI)

P

Adjusted OR (95% CI)

P

Maternal age(per year)

0.97(0.88–1.06)

0.496

1.01(0.91–1.11)

0.923

Maternal HBV DNA(per log)

1.19(0.83–1.70)

0.348

1.28(0.90–1.83)

0.165

Infant gender(F/M)

1.32(0.60–2.90)

0.488

1.18(0.53–2.65)

0.691

HBIG dose(200 IU/100 IU)

1.11(0.45–2.72)

0.822

0.64(0.22–1.87)

0.410

Immunoprophylaxis pattern

 

0.033

 

0.014

10 μg HB vaccine without booster

ref

 

ref

 

20 μg HB vaccine without booter

0.39(0.16–0.97)

0.043

0.26(0.09–0.78)

0.016

10 μg HB vaccine with booster

0.22(0.45–1.00)

0.050

0.21(0.05–0.97)

0.046

20 μg HB vaccine with booster

0.24(0.67–0.87)

0.030

0.17(0.04–0.68)

0.013

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