The conversion of a deuterated substrate into cellular metabolites in vivo can be quantified via decreases in the proton nuclear magnetic resonance signals of these metabolites.
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van Zijl, P.C.M., Brindle, K.M. Spectroscopic measurements of metabolic fluxes. Nat Biomed Eng 4, 254–256 (2020). https://doi.org/10.1038/s41551-020-0535-8
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DOI: https://doi.org/10.1038/s41551-020-0535-8
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