Extended Data Fig. 2: COL3A1, S100A4, SM22A, ACTA2, FBLN2, and SDC4 are expressed by peri-implant fibrotic tissue in both human and mice. | Nature Biomedical Engineering

Extended Data Fig. 2: COL3A1, S100A4, SM22A, ACTA2, FBLN2, and SDC4 are expressed by peri-implant fibrotic tissue in both human and mice.

From: Prevention and treatment of peri-implant fibrosis by functionally inhibiting skeletal cells expressing the leptin receptor

Extended Data Fig. 2

Expression of COL3A1 (a, green), S100A4 (c, green), SM22A (e, green), ACTA2-RFP (g, green), FBLN2 (i, green), SDC4 (k, green) in murine peri-implant fibrotic tissue and its overlap with LepR– tdTomato cells (red). Scale bar, 50 μm. Expression of COL3A1 (b, green), S100A4 (d, green), SM22A (f, green), ACTA2 (h, green), FBLN2 (j, green), SDC4 (l, green) in human peri-implant fibrotic tissue and its overlap with LEPR+ cells (red). Scale bar, 50 μm. Images in a–l are representative of at least 3 independent biological replicates.

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