Extended Data Fig. 5: Additional comparison of BitSeq with commercial sequencers in resequencing.
From: A fuzzy sequencer for rapid DNA fragment counting and genotyping
(a, b) The normalized sequencing depth of a normal male adult by BitSeq (a) and Ion Torrent (b). (c, d) The normalized sequencing depth of a Trisomy 21 patient by BitSeq (c) and Ion Torrent (d). (e) The average sequencing depth of ChrY of each sample. These values by both BitSeq and ion torrent differ substantially between male and female fetuses. (f) Number of genes detected using different thresholds for RNA-seq data of mES and MEF cells. (g) Venn diagram of TPM > 1 genes. (h, j) Gene Ontology analysis of genes that were only detected by each sequencer in RNA-seq.
