Extended Data Fig. 2: Complex 1 sensitized RT effectively inhibits the growth and metastasis of 4T1 tumours.
a, Schemes of 4T1 tumour inoculation and therapies. b, Tumour growth curves of each mouse. c, Average tumour growth curves showed 1 sensitized RT effectively inhibited the growth of 4T1 tumours (n = 9). Tumour growth with the passage of time was compared by two-way ANOVA (Tukey’s test). d, Survival curves showed 1 sensitized RT prolonged the survival time of mice (n = 9). Differences in survival were determined for each group by the Kaplan-Meier method, and the overall P value was calculated by the log-rank test. e, Representative lung pathology sections of mice showed that 1 sensitized RT effectively inhibited lung metastasis of 4T1 tumours. Black arrow, pulmonary nodules. f, Lung metastasis count of mice (n = 3). One-way ANOVA multiple comparisons (Tukey’s multiple comparisons test) were used when more than two groups were compared. All the values in the present study are presented as the mean ± s.d., and all replicates are biological independent samples.
