Supplementary Figure 3: The relationship between the expression of claudin family members and Snail.
From: Snail-induced claudin-11 prompts collective migration for tumour progression
(a) RT-qPCR analysis of CLDN3, CLDN4, CLDN7, and SNAI1 in primary HNSCC cells expressing control (pCDH), wild-type Snail (Snail-WT) or unacetylatable Snail (Snail-2R). Caco2 cells was used as a positive control for the expressions of CLDN3, CLDN4 and CLDN7 (n = 2 independent experiments). Data represent mean values. (b) Western blots for showing claudin-3, -4, -7, and Snail in primary HNSCC cells expressing control (pCDH), wild-type Snail (Snail-WT) or unacetylatable Snail (Snail-2R). Caco2 cells was used as a positive control for the expressions of claudin-3, -4, and -7. β-actin was a loading control. The data was from one experiment. Uncropped images of all blots are shown in Supplementary Figure 8. Source data is provided in Supplementary Table 11.
