Extended Data Fig. 6: Expansion of Gli1 Lin + mesenchyme into the alveoli. | Nature Cell Biology

Extended Data Fig. 6: Expansion of Gli1 Lin + mesenchyme into the alveoli.

From: Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung

Extended Data Fig. 6

(a) Multi-colour stochastic recombination of Gli1 Lin+ cells tagged with one of four possible fluorescent proteins (GFP, YFP, RFP, or CFP) shows clones of single color clustering around the airway in PBS treated lungs, and clones of single color spanning the airway and alveoli following bleomycin injury (4 animals per group) (b) Violin plots showing retention of Gli1 expression in Gli1 Lin+ cells following bleomycin injury as they migrate into the alveoli. Each black dot represents one cell (n values listed in source data for Fig. 4d). AW = airway. Scale bars, 100 μm.

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