Extended Data Fig. 7: Single cell characterization of stromal components. | Nature Cell Biology

Extended Data Fig. 7: Single cell characterization of stromal components.

From: Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

Extended Data Fig. 7: Single cell characterization of stromal components.

a, Hierarchical clustering using all subtype marker genes, color coded by subtypes. b, Correlation between EMT score in epithelial cells and percentage of ACTA2+ CAF. Two-sided P values calculated for Spearman’s rank correlation and not adjusted for multiple comparisons. c, tSNE view CAF cells, color coded by activation level of the indicated TFs (AUC). d, Overlap of the unique incoming cell communication pairs from epithelial cells to fibroblast, regular EC and aEC. e, Top 5 most enriched pathways for each cluster.

Back to article page