Extended Data Fig. 7: Flt1 +67 kb and Maml3 +360 kb enhancers.

a,b, Genome browser tracks showing the Flt1 (a) and the Maml3 (b) loci. Black arrowheads indicate the Flt1 +67 kb (top) and the Maml3 +360 kb (bottom) enhancers. Tracks correspond to the snATAC-seq profiles of the erythroid, endothelium and allantois cell types after cell pooling, TAL1 ChIP-seq for haemogenic endothelial cells (“HE TAL1 ChIP-seq”, grey), H3K27ac ChIP-seq for haemogenic endothelial cells (“HE H3K27ac”, gold), TAL1 ChIP-seq for haemangioblasts (“Haem. TAL1 ChIP-seq”, grey), H3K27ac ChIP-seq for haemangioblasts (“Haem. H3K27ac”, gold), TAL1 ChIP-seq for haematopoietic progenitors (“HP TAL1 ChIP-seq”, grey), H3K27ac ChIP-seq for haematopoietic progenitors (“HP H3K27ac”, gold) from³², TAL1 ChIP-seq for HPC-7 cells (“HPC-7 TAL1 ChIP-seq”, grey) and DNase-seq for HPC-7 cells (blue). Publicly available tracks were obtained from http://codex.stemcells.cam.ac.uk/.