Extended Data Fig. 7: At limiting dynein concentration, Lis1 recruits single dynein to dynactin and BicD2N.
From: Lis1 activates dynein motility by modulating its pairing with dynactin
a, Schematic depiction of wtDDB assembly using 5 nM LD650-wtDyn and TMR-wtDyn in the absence and presence of 600 nM Lis1. b, Fraction of processive and static/diffusive wtDDB complexes on MTs (mean ± SEM, n = 59, 788, 303 and 984 from left to right, three independent experiments).Â
