Extended Data Fig. 5: FBXL7 protein expression inversely correlates with c-SRC protein expression in pancreatic and prostate cancer. | Nature Cell Biology

Extended Data Fig. 5: FBXL7 protein expression inversely correlates with c-SRC protein expression in pancreatic and prostate cancer.

From: Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis

Extended Data Fig. 5

a, Representative immunohistochemistry staining images of normal (N) and tumor human pancreatic specimens at different disease stage. Levels of FBXL7 and c-SRC protein in consecutive tissue slides are shown. n = 5 (N) and n = 66 (tumor) independent specimens. Scale bar: 100 μm. b, Representative immunohistochemistry staining images of normal (N) and tumor prostate human specimens at different disease stage. Levels of FBXL7 and c-SRC protein in consecutive tissue slides are shown. n = 10 (N) and n = 84 (tumor) independent specimens. Scale bar: 100 μm.

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