Extended Data Fig. 2: nPD-L1-mediated pyroptotic cell death in cell lines of multiple cancer types. | Nature Cell Biology

Extended Data Fig. 2: nPD-L1-mediated pyroptotic cell death in cell lines of multiple cancer types.

From: PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

Extended Data Fig. 2

(a) Immunoblotting analysis of PD-L1 expression levels in liver cancer and lung cancer cell lines. Blots are representative of three independent experiments. (b) Hypoxia-induced pyroptotic cell death in PD-L1-positive cells of multiple cancer types treated with p-Stat3 inhibitor, HO-3867. Red arrows indicate the pyroptotic cells with big bubbles. The experiment was repeated three times with similar results. Scale bar, 20 μm. Unprocessed blots are provided in Source Data Extended Data Fig. 2.

Source data

Back to article page