Extended Data Fig. 9: Proteome analysis of Ago2-null oocytes.
From: Global profiling of RNA-binding protein target sites by LACE-seq
a, The mass spectrometry data were highly correlated in two biological replicates. b, The fold change and significance of the Calm1, Nuf2, Chk1, and Bub3 protein levels as revealed by mass spectrometry in Ago2-null oocytes. c, The predicted miRNA density (miRNA counts/mRNA length×1000) showing no correlation with the protein level changes upon Ago2 ablation in oocytes. P-value was calculated by two-tailed Kolmogorov-Smirnov test. d, The percentage of LTR-driven and upregulated chimeric proteins detected by mass spectrometry. e, The fold change in MS-detected (17.6%) and LTR-derived chimeric proteins in Ago2-null oocytes. MS data in b-e represent results from two independent experiments.
