Extended Data Fig. 3: Spermatogenesis defects in Piwil1- and Mov10l1-deficient golden hamsters.
From: The piRNA pathway is essential for generating functional oocytes in golden hamsters
(a) Comparison of the testes from 8-week-old wild-type, Piwil1m1/m1, Piwil1m2/m2 and Mov10l1ins1/ins1 golden hamsters. (b) The testis/body weight ratios. Testes were collected from 8-week-old wild-type, Piwil1w/m1, Piwil1m1/m1 and Mov10l1ins1/ins1 golden hamsters. Data are presented as mean values ± s.e.m. Statistical analysis was performed using unpaired two-tailed t-test. n = 4 Piwil1 mutants or n = 5 Mov10l1 mutants. (c-d) Periodic acid-Schiff (PAS) staining of adult caput epididymis (c), cauda epididymis (d). (e) H&E staining of WT and Mov10l1ins1/ins1 testes at 8, 14, 28, and 42 days post partum (d.p.p.). The assays in c, d and e were independently repeated twice and showed similar results. Statistical data are provided in the source data.
