Extended Data Fig. 8: The effect of MLL3 loss on genome-wide changes of H3K27ac, H3K4me1 and H3K4me3 in MCF7 and MDA-MB-231 cells.
From: MLL3 loss drives metastasis by promoting a hybrid epithelial–mesenchymal transition state
a, Heatmaps of ChIP-seq signals for the indicated histone marks and ATAC-seq signals in a 6 kb window grouped by localization at the promoter, intron, and intergenic regions in sgNT or sgMLL3 MDA-MB-231 cells. b, Western blot analysis of protein levels of H3K27ac, H3K4me1, and H3K4me3 in sgNT or sgMLL3 MCF7 and MDA-MB-231 cells (n = 2 independent experiments).
