Extended Data Fig. 3: FIB-SEM reveals ER tubules in physical contact with the desmosome outer dense plaque. | Nature Cell Biology

Extended Data Fig. 3: FIB-SEM reveals ER tubules in physical contact with the desmosome outer dense plaque.

From: Architecture and dynamics of a desmosome–endoplasmic reticulum complex

Extended Data Fig. 3

(a–c) Orthoslices in XY (A), XZ (B), and YZ (C) showing ER tubules making physical contact with desmosome outer dense plaque. (d–f) Same orthoslices as in A-C with ER, keratin, and desmosome segmentations. Yellow arrows point to physical contact between ER tubules and the desmosome outer dense plaque in all 3 views. Images are representative of n = 1 cell-cell contact. Scale bar = 250 nm.

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