Extended Data Fig. 1: Identification of human CM-specific lncRNA LIPTER (LINC00881).
From: Lipid droplet-associated lncRNA LIPTER preserves cardiac lipid metabolism
a, RT-qPCR detection of pluripotency marker OCT4, cardiac progenitor marker PDGFRA, cardiomyocyte marker TNNT2, endothelial cell marker CD31, smooth muscle cell marker SM22, as well as lncRNAs NAV2-AS2, TTN-AS1 and SLC8A1-AS1 expressions in enriched cardiovascular cell types differentiated from human iPS cells. (n = 2 independent experiments). b, RT-qPCR detection of lncRNAs NAV2-AS2, TTN-AS1 and SLC8A1-AS1 expression levels in left ventricle tissues from NF (n = 10 samples), NF+T2DM (n = 4 samples), DCM (n = 12 samples) and DCM+T2DM (n = 5 samples) individuals. All bars are presented as mean ± s.e.m. Unpaired two-tailed t-test is used for comparison. c, Histogram of LINC00881 expressions in the human hearts during fetal development. RPKM, Reads Per Kilobase of transcript (RPKM). Bars are presented as mean ± sd. Data were analyzed from GSE6428373. d, Histogram of LINC00881 expressions across 20 human tissues. Data were analyzed from NCBI Accession PRJNA28060074. e, Histogram of LINC00881 expressions across 16 human tissues. Data were analyzed from GSE30611 (Illumina Human Body Map 2.0 Project). Source numerical data are available in source data.
