Extended Data Fig. 2: Reconstituted GFP-TAZ condensates exhibit liquid-like properties and are associated with FUS and several other hits.
From: A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation
a, Time-lapse imaging of GFP-TAZ droplets formed in NE. The arrows indicate the spontaneous fusion event of GFP-TAZ droplets over time. b, Gene Ontology analysis of the MS-identified proteins that preferentially associated with reconstituted GFP-TAZ droplets in NE. c, Cells expressing GFP-TAZ together with mCherry or mCherry-FUS were examined by fluorescence microscopy. DNA was counterstained by Hoechst. Scale bar, 10 μm. d, Cells expressing GFP-TAZ together with mCherry-tagged fusion proteins were examined by fluorescence microscopy. DNA was counterstained by Hoechst. Scale bar, 10 μm.
