Extended Data Fig. 6: Mice lacking EPAC1 in PDGFRα+ cells.
From: EPAC1 enhances brown fat growth and beige adipogenesis
a, Oxygen consumption at 23 °C of Epac1fl/fl PdgfraCre/+ (EPAC1PKO) and Epac1fl/fl Pdgfra+/+ (WT) mice over the course of 24 hours, n = 12 (WT), n = 15 (EPAC1PKO) independent animals. b, Body weight of mice exposed for 1 week at 4 °C, n = 10 independent animals. c-d, Body core temperature was continuously measured using an implanted mouse telemetry system. n = 4 (WT), n = 6 (EPAC1PKO) independent animals. c, Body temperature over time; d, AUC of day and night cycles were calculated during the cold exposed time. P values determined by unpaired two-tailed t-test. Data are presented as mean values ± SEM. Source numerical data are available in source data.
