Extended Data Fig. 2: Pathway expression over time and commonly used pathways.
From: FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy
(a) Log2FC (mTORi/normal) of mean protein expression (mTORi/control t = 0) of each KEGG pathway at each time point in ESCs vs TSCs. Note that an initial concordant response can be seen for the first 12 h, which is lost afterwards. (b) Change in pathway expression over time in ESCs vs TSCs in response to mTORi treatment, computed by a linear regression of the mean KEGG pathway protein expression. (c) Concordantly altered KEGG pathways in ESCs and TSCs in response to mTORi.
