Extended Data Fig. 9: Top candidate regulators of domain identity. | Nature Cell Biology

Extended Data Fig. 9: Top candidate regulators of domain identity.

From: Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains

Extended Data Fig. 9: Top candidate regulators of domain identity.The alternative text for this image may have been generated using AI.

a,b Domain-wise expression levels of 5 candidate regulators of domain A and B identities (a) and 15 candidate regulators of domain D and E identities (b), identified using ChEA3 and SCENIC analyses. c,d Expression trajectories of indicated factors, coloured according to inferred differentiation stage in Fig. 6c. Transcription factor expression trajectories were plotted for cells in domain E. Plots are grouped according to expression by early-lineage cells (c) or differentiated cells (d).

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