Fig. 4: A map of cell fate decisions in fetal human frontal cortex.
a, Live/fixed correlative analysis of a dividing bRG cell generating a bRG daughter and an IP daughter. b, Summary of all division patterns identified in bRG cells at GW 14 (N = 170 bRG cells) human frontal cortex. c, Proportion of proliferative versus neurogenic divisions of bRG cells in GW 14 and 18 human fetal tissue. d, Proportion of asymmetric (self-renewing) versus symmetric (self-consuming) neurogenic divisions of bRG cells in GW 14 and 18 human fetal tissue. e, Proportion of direct versus indirect neurogenic divisions of bRG cells in GW 14 and 18 human fetal tissue. f, Spatial distribution of proliferative versus neurogenic (left), self-consuming versus asymmetric self-renewing (middle) and direct versus indirect neurogenic divisions (right) in GW 17 human frontal cortex. g, Quantification of proliferative versus neurogenic (left), self-consuming versus asymmetric self-renewing (middle) and direct versus indirect neurogenic divisions (right) in GW 17–18 human frontal cortex (N = 355 cells for GW 17 and 172 cells for GW 18). Data are presented as mean values. Images are representative examples of experiments performed in at least two independent fetal brains.
