Extended Data Fig. 2: Live/fixed correlative examples and cell fate identification timing in cerebral organoids. | Nature Cell Biology

Extended Data Fig. 2: Live/fixed correlative examples and cell fate identification timing in cerebral organoids.

From: A cell fate decision map reveals abundant direct neurogenesis bypassing intermediate progenitors in the human developing neocortex

Extended Data Fig. 2: Live/fixed correlative examples and cell fate identification timing in cerebral organoids.

a, Detection of bRG, IP or neuronal cell fate relative to the time of division of the bRG mother cell in cerebral organoids at week 8-10 (873 cells from N = 5 organoid batches). b, (Top) Live/fixed correlative analysis of a dividing bRG cell generating two IP daughters. (Bottom). Live/fixed correlative analysis of a dividing bRG cell generating two bRG daughters. c, Live/fixed correlative analysis of a dividing bRG cell generating a bRG daughter and a neuronal daughter. Data are presented as mean values +/- SD. All images are representative examples of experiments performed in at least 3 independent organoid batches.

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