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Temporal dynamics of membrane contact sites

Nature Cell Biology volume 26, pages 1822–1824 (2024)Cite this article

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Cell behaviour changes temporally in response to environmental and metabolic cues. This also applies to membrane contact sites (MCSs), where organelles come into close proximity to perform specific functions, such as lipid transfer or calcium signalling. Here, we discuss how MCSs change over time and whether MCSs exhibit circadian rhythmicity.

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Fig. 1: Schematic representation of the changes occurring between two organelles, labelled A and B.

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Acknowledgements

T.K. is grateful to the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement for financial support (no. 896745). M.G. is grateful to the LEO Foundation for financial support (LF-OC-20-000630 and LF-SE-23-800010).

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  1. Department of Biology, University of Padua, Padua, Italy

    Tomas Knedlik & Marta Giacomello

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  1. Tomas Knedlik
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  2. Marta Giacomello
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Correspondence to Marta Giacomello.

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The authors declare no competing interests.

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Nature Cell Biology thanks the anonymous reviewers for their contribution to the peer review of this work.

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Knedlik, T., Giacomello, M. Temporal dynamics of membrane contact sites. Nat Cell Biol 26, 1822–1824 (2024). https://doi.org/10.1038/s41556-024-01539-z

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