Extended Data Fig. 8: Flow velocity near the chromosomes correlates with chromosome velocity across all cell sizes. | Nature Cell Biology

Extended Data Fig. 8: Flow velocity near the chromosomes correlates with chromosome velocity across all cell sizes.

From: Cytoplasmic flow is a cell size sensor that scales anaphase

Extended Data Fig. 8

a-g, Correlation of flow velocity near each set of chromosomes in anaphase and the velocity of chromosomes themselves. Each dot in the graph corresponds to the correlation in one time point in the 100–200 s after anaphase time window. n = 17, 15, 22, 6, 10, 6 and 10 PIV measurements x 10 time points, corresponding to the 100–200 s after anaphase time window, from 7, 8, 8, 3, 5, 3, 5 embryos at 4-, 8-, 16-,32-,64-,128-cell stages, respectively. For each cell, there can be up to two vorticity measurements corresponding to the sets of segregating chromosomes in the dividing cell. h, Flow velocity at the spindle midzone region versus chromosome velocity. Velocities are not correlated. n = 15 PIV measurments, from 8 embryos at 4-cell stage. i, Angle difference between chromosomes and the flow at the spindle midzone region, for the same dataset as in (h).

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