Extended Data Fig. 6: Surface conjugation with DNA duplexes for measuring the thickness of an acidic layer.
From: DNA nanodevices detect an acidic nanolayer on the lysosomal surface
a, Schematic illustration of liposomes anchored with 15-bp, 29-bp, or 52-bp DNA duplex; Right panels show the Dynamic Light Scattering (DLS) profiles of a naked liposome and liposomes conjugated with DNA duplexes of given base pair numbers. b, Correlative analysis of the liposomal diameter versus the number of DNA base pairs (n = 3 independent experiments). c, Summary of DNA duplex thickness on the liposomal surface (n = 3 independent experiments). For all panels, statistical data are presented as mean ± s.d. Two-tailed Student’s t test was used to assess statistical significance.
