Extended Data Fig. 8: ODM-seq PCA analysis.

a, PCA as shown in Fig. 6f, but with individual biological and technical replicates. The 180 and 240 min incubation times with M.SssI were in saturation (Extended Data Fig. 6a) and could therefore serve as technical replicates. b, Examining PCA for the downstream flank of the +1 nucleosome. This PCA is as in Fig. 6f, but for the downstream flank of the +1 nucleosome (Extended Data Fig. 7g). c, As in b, but for the biological and technical replicates individually (see a). d, PCA as in Fig. 6f, but for the NFR window (Extended Data Fig. 7g). e, As in d, but for the biological and technical replicates individually (see a).