Extended Data Fig. 7: Parameter sweep analysis for the impact of mutation and fusion rates on clonal richness.
From: Spontaneous cell fusions as a mechanism of parasexual recombination in tumour cell populations
Graphs depict results of in silico simulations with branching birth-death model showing clonal richness over time for the indicated mutation (ÎĽ) and fusion (f) rates; p values indicate the results of Kolmogorov-Smirnov test comparing clonal richness at the end of the simulation (only shown for differences that has reached the 0.05 significance threshold); growth rate a=0.67/day; carrying capacity K=104 cells; number of genes G=300.
