Extended Data Fig. 3: Phenotypic characterization of hybrid cells.
From: Spontaneous cell fusions as a mechanism of parasexual recombination in tumour cell populations
a. Growth rates of the indicated cell lines and their hybrids, at the indicated passages post-antibiotic-selection. b. Representative images of stained membranes from Boyden chamber cell invasion/migration assay. c. Quantitation of Boyden chamber cell invasion/migration assay data. d. Quantification of area of lung metastases formed after tail vein injection of MCFDCIS and MCFDCIS/SUM159PT hybrids. Data from individual mice are plotted separately. *, **, ***, *** denote p values below 0.05, 0.01, 0.001 and 0.0001, respectively, for the two-tailed unpaired t-test. Error bars represent SD, dots represent biological replicates (a,c,d).
