Extended Data Fig. 10: Symbiont and bleached metabolome relationships with bleaching history and molecular family responses to heat stress.

PCA of all metabolites found in replicate symbiont pellets (a) and all metabolites found in replicate bleached host fragments (b). These samples were collected from colony 19 and 20, which are included in the larger lab dataset and represent a bleached and non-bleached colony, respectively. Fill represents HBP (gray = non-bleached, white = bleached). Multivariate response to heat stress for (c) Membrane Lipids and (d) Bioactive Molecules (e) Putative Microbial Products. Fill represents HBP (gray = non-bleached, white = bleached). Color represents initial and heat stress timepoints (black = initial, red = heat stress). Gray ellipses represent 95% confidence interval of phenotypes. Gray bars connect paired before-after samples.