Extended Data Fig. 6: Oxford grid between bony vertebrate chromosomes and chordate linkage groups (CLGs).
From: Deeply conserved synteny resolves early events in vertebrate evolution

Circles represent the number of orthologous genes between human (Homo sapiens, HSA), chicken (Gallus gallus, GGA), frog (Xenopus tropicalis, XTR), and spotted gar (Lepisosteus oculatus, LOC) and the seventeen chordate linkage groups (CLGs) described in the text. Orthology is operationally defined by mutual best hits, restricted to 6,843 gene families anchored by mutual best hits of the four jawed vertebrates to amphioxus. The area of each circle is proportional to the number of orthologous genes for each chromosome-CLG pair, and the color indicates the significance of the association relative to a null model in which the position of the orthologous genes are randomly shuffled (Methods).