Extended Data Fig. 2: Deletions induced by vg and apA CRISPR/Cas9 KO.

a, vg KO2 alignments. b, vg KO3 alignments. c, apA KO2 alignments. d, apA KO3 alignment. The top line in each alignment shows the WT sequence with the targeted site (green) and the Protospacer adjacent motif (PAM) (blue highlight). Red in brackets with “Δ” indicates the number of base pairs deleted from that region and blue in brackets with “+” indicates the number of base pairs added to that region. Yellow nucleotides indicate SNPs.