Extended Data Fig. 2: Relative ratio of wGII score, necrosis and proportion of regions containing grade 4 ccRCC using different cut-off values for defining tumour centre and margin.
From: Selection of metastasis competent subclones in the tumour interior
Relative ratio of wGII score, necrosis and proportion of regions containing grade 4 ccRCC using different cut-off values for defining tumour centre and margin. Median wGII score of tumour centre divided by median wGII score of tumour margin was shown in green, frequency of regions containing necrosis in the tumour centre divided by frequency of regions containing necrosis in the tumour margin was shown in red, frequency of regions containing pathological grade 4 ccRCC in the tumour centre divided by frequency of regions containing pathological grade 4 ccRCC in the tumour margin was shown in purple, and frequency of regions containing metastasizing clones in the tumour centre divided by frequency of regions containing metastasizing clones in the tumour margin was shown in grey.
