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EVOLUTIONARY THEORY

Antigenic evolution can drive virulence evolution

Repeated epidemic waves, characteristic of an antigenically evolving pathogen, can drive selection for higher pathogen virulence

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Fig. 1: How epidemiological dynamics with or without antigenic variation drive virulence evolution.

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Correspondence to Nicole Mideo.

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Mideo, N., Kamiya, T. Antigenic evolution can drive virulence evolution. Nat Ecol Evol 6, 24–25 (2022). https://doi.org/10.1038/s41559-021-01600-2

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