Extended Data Fig. 6: The distribution of duplicates across different chromosomes and distribution of distances to HASs. | Nature Ecology & Evolution

Extended Data Fig. 6: The distribution of duplicates across different chromosomes and distribution of distances to HASs.

From: Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans

Extended Data Fig. 6: The distribution of duplicates across different chromosomes and distribution of distances to HASs.

a) Chromosomal distribution of duplicates. We only included the major autosomes (Drosophila: 2 L, 2 R, 3 L, 3 R; Human: 1-22) and the X chromosome in the calculation. The proportion of annotated coding genes on each chromosome in the reference genome is used as the control (BG or background). The P was calculated with the one-sided proportion test. b) distances to HASs. The median distance (28,687 bp) of 8 complete duplicates relative to the closest HAS was highlighted with a green line. We generated 10,000 random samples and calculated the empirical P as the percentage of how many times random samples showed a shorter median distance. The blue line indicates the median value of random samples. The two median values are also shown.

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