Extended Data Fig. 3: Changes in mutator frequency are driven by indirect selection. | Nature Ecology & Evolution

Extended Data Fig. 3: Changes in mutator frequency are driven by indirect selection.

From: Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs

Extended Data Fig. 3

Boxplots depicting temporal changes in relative mutator fitness (𝑣) as a function of community absence and presence. We determined relative mutator fitness (𝑣) by comparing mutator frequencies between consecutive time points, using: 𝑣 = x2(1-x1)/x1(1-x2), where x1 x1 is mutator frequency at transfer (tn) and x2 mutator frequency at transfer (tn+1). Boxes depict the upper and lower quartiles of the treatment-specific raw data with the centre line showing the median and whiskers providing a measure of the 1.5x interquartile range. Dots represent individual replicate populations (n = 12 per community treatment). See Extended Data Fig. 4 for associated model predictions and diagnostics.

Source data

Back to article page