Extended Data Fig. 2: Scaling down number of L. variegatus cells does not substantially affect clustering.

UMAP of non-integrated single cell RNA-seq data from L. variegatus, in which the data has been randomly subsampled to 2065 cells so that the cell number is equivalent to the H. erythrogramma dataset. This subsampling does not change the number and general spatial relationship among clusters in L. variegatus (that is distinct cluster of skeletogenic cells separate from remainder of cells in the embryo).