Extended Data Fig. 4: Expression vs. number of SNPs detected.
From: Transcriptional and mutational signatures of the Drosophila ageing germline
We averaged the expression of every gene across every replicate and then compared the number of SNPs detected within genes with lower than mean expression (‘Low expression’, n = 310) with genes with expression greater than the mean expression of all genes (‘High expression’, n = 1488). For each group we compared genes with a two-sided Wilcoxon test, then adjusted p values with Bonferroni’s correction. There are significantly more mutations in lowly expressed genes in every replicate. Boxes represent the 75th to 25th percentiles, the top whisker represents the largest value within 1.5 times the interquartile range, and the bottom whisker represents the smallest value within 1.5 times the interquartile range of the 25th percentile.
