Extended Data Fig. 5: Neuropeptide signaling in spiders.
From: Single-cell transcriptomics reveals the brain evolution of web-building spiders
a, Comparison of proportion of the gene number of neuropeptides between marker gene list and all genes. Significance was calculated using two-sided Chi-square test. b-c, The major outgoing (b) and incoming (c) neuropeptide signals across the 42 brain cell clusters. d, The communication networks of two dominant neuropeptide signals (Mip and DH31). e-h, Cell communications strength in male and female of spiders. Cell communication patterns between males and females are similar. But several signals showed sexual difference. i, Examples of large clusters (ncells >500) that expressed neuropeptides. j, Expression patterns of neuropeptides and neuropeptide receptors across different tissues. Expression level was column-scaled for comparisons.
