Extended Data Fig. 9: Mammalian-specific genes may drive cell type specialization. | Nature Ecology & Evolution

Extended Data Fig. 9: Mammalian-specific genes may drive cell type specialization.

From: Origin and stepwise evolution of vertebrate lungs

Extended Data Fig. 9

a, Phylogenetic tree illustrating the origin of the sfta2 gene from a duplication of the rhcg gene. b, Phylogenetic tree illustrating the origin of the scgb3a2 gene. c, Enrichment analysis of genes upregulated in the lungs of sfta2 knockout homozygous mice. The plot shows enriched GO terms, ReactomeDB pathways, and WikiPathways, with dot size indicating gene count and color representing significance.

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