Extended Data Fig. 1: Comparative analysis of cell types and gene expressions across vertebrate species using single-cell RNA sequencing data. | Nature Ecology & Evolution

Extended Data Fig. 1: Comparative analysis of cell types and gene expressions across vertebrate species using single-cell RNA sequencing data.

From: Origin and stepwise evolution of vertebrate lungs

Extended Data Fig. 1

This figure displays a phylogenetic tree of various species (from Senegal bichir to rat), with corresponding cell counts and UMAP plots showing cell type clustering. Each species’ plot is color-coded to represent different cell types, belonging to immune, stromal, endothelial and epithelial cells. Adjacent to the UMAP plots, a dot plot heatmap illustrates gene expression patterns across cell types, with dot size indicating the percentage of cells expressing each gene and color intensity showing expression levels. The UMAP plots for pig, human, mouse, and rat are provided at the bottom. The light color block highlights the data generated for this study.

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