Extended Data Fig. 4: The expected vs observed cumulative distribution of population hits across the 10 S. pombe populations.
We defined population hits (PH) as the number of populations in which a gene has a hit. The null model assumes that all genes evolve and fix variants at the same rate, so the expected PH is determined by this assumption and follows a Poisson distribution (Methods). The one-sided p-values were obtained using a Kolmogorov-Smirnov test (alternative: cumulative distribution function 1 is “higher” than function 2, which means that there are higher values in function 2).
