Extended Data Fig. 1: Pressure mapping of the FUS transducers operating at different frequencies.

a-d, Acoustic pressure fields in both the lateral (x–y plane at z0 = 0, i) and axial (y–z plane, at x0 = 0, ii) planes for a 0.65-MHz transducer (a), 1.5-MHz transducer (b), 3.3-MHz transducer (c), and 5.7-MHz transducer (d). In each panel, subpanels iii and iv display the corresponding spatial pressure profiles across the dashed lines in i and ii, respectively. FWHM was used to quantify the lateral resolution, while the depth of focus (DOF), defined as the −6 dB pressure width, was used to quantify the axial resolution.