Fig. 3: Histological examination of the teat cistern and mammary alveoli following primary inoculation. | Nature Microbiology

Fig. 3: Histological examination of the teat cistern and mammary alveoli following primary inoculation.

From: Dairy cows develop protective immunity against reinfection with bovine H5N1 influenza virus

Fig. 3: Histological examination of the teat cistern and mammary alveoli following primary inoculation.

Cow #6 was euthanized at 4 days post inoculation. Representative H&E staining is shown for the teat cistern and mammary alveoli for each quarter, including an intralobular duct from the forequarter and hindquarter. Inoculated hindquarters (HR, HL) show severe acute necrotic mastitis with alveoli filled with proteinaceous material mixed with fat droplets. Images were captured at ×200 magnification, insets are digital magnifications of the boxed area. Cow schematic illustrating anatomical location of each quarter of the udder; mammary gland schematic shows tissue sampled for histological examination. Select figure elements were generated using BioRender.com.

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