Extended Data Fig. 8: Biosafety accessing of optoelectronic capsule.

(a) Detection of extra heat generated from optoelectronic capsule with LED switching on and off when placed in an incubator mimicking body temperature. (b) Scheme of biosafety accessing of optoelectronic capsule in pig body. Several blood indicators were detected before and after the two rounds of capsule ingestion for 4 days each round. (c) Comparison of pathological images of the pigs taking optoelectronic capsule or not. Sclar Bar=200μm. (d)–(g) Detection of the levels of C-reactive protein (CRP), hemoglobin (HGB), leukocyte, and platelet before and after the ingestion of optoelectronic capsule. The relatively normal parameter value range was shown in each figure by dashed line. All the measurements in the above experiments were taken from distinct biological replicates. Data are presented as the mean ± SD. n = 3. Significance was determined according to unpaired, two-tailed student’s t-test for (a). The significance labelled as ‘ns’ meant p > 0.05 Source data. Panel b created with BioRender.com.