Extended Data Fig. 8: Linoleic acid promotes the formation of mitochondria-associated ER membranes (MAMs). | Nature Microbiology

Extended Data Fig. 8: Linoleic acid promotes the formation of mitochondria-associated ER membranes (MAMs).

From: Mycobacterium tuberculosis-derived linoleic acid increases regulatory T cell function to promote bacterial survival within macrophages

Extended Data Fig. 8: Linoleic acid promotes the formation of mitochondria-associated ER membranes (MAMs).

Naïve CD4+ T cells were stimulated with anti-CD3 and anti-CD28 antibodies in the presence of IL-2 and TGF-β for 3 days and treated with or without linoleic acid (100 μM). Immunofluorescence data shows Hoechst (Blue), Mito-Traker (Green), and ER-Traker (Magenta) staining in CD4+ Tregs. Right, pixel intensity plot for dashed line. Scale bar = 1 μm. Data of a represents one experiment with three independent biological replicates (n = 3).

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