Extended Data Fig. 4: Complexome maps vs local subnetworks.
From: MAP-X reveals distinct protein complex dynamics across Plasmodium falciparum blood stages
a, Number of known co-clustering protein complex subunits in global maps (GM) and local subnetworks (LS) across different timepoints shows that local subnetworks retrieve additional unmapped interactions. b, Comparison of proportion of co-clustering subunits for different known protein complexes between GM and LS. c-g, Integration check PCR on genomic DNA from 3D7 and the indicated cell lines to validate correct integration of the SLI plasmid at the 3’- and 5’-end and disruption of the original locus (WT locus); PF3D7_1149100 (c), PTP7 (d), PF3D7_1149100 with PTP7 background (e), CCZ1 (f) and RMC1 (g). The PCR results are representative of results from three different clones. One clone was always chosen for the subsequent experiments. h Western blot of GST and GST-ALBA1/3 bound to Glutathione Sepharose resin confirming the presence of bait for interaction assays.
